Kutatási jelek – Signal Engine

• ROR1-PI3K/AKT signaling drives adaptive resistance to cell cycle blockade in TP53 mutated ovarian cancer — Ovarian cancer
• Long‑term survival with nivolumab in a patient with renal cell carcinoma: a case report and review of the literature — Renal cell carcinoma
• HER2 Expression and Nuclear Localization in Clear Cell Renal Cell Carcinoma: Implications for Prognosis and Therapeutic Targeting — Renal cell carcinoma
• Ipilimumab and nivolumab followed by chemoradiotherapy as bladder-sparing treatment in muscle-invasive bladder cancer: a phase 2 trial — Bladder cancer
• Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure — Colorectal cancer
• EGFR and AR expression and co-expression in Indian triple-negative breast cancer with patient outcome association — Breast cancer
• The Crosstalk Mechanism of EGFR and ER in EGFR-Mutant Lung Adenocarcinoma — NSCLC
• TGF-α/EGFR-mediated lymphatic metastasis reveals a repositionable therapeutic target in breast cancer — Breast cancer
• Osimertinib activates TFEB to trigger hepatocyte cytoplasmic vacuolation-associated cell death — NSCLC
• Genomics of Primary and Metastatic Cutaneous Melanoma: A Systematic Review and Meta-Analysis — Melanoma
• Detection of mutated KRAS, TP53, CDKN2A, and SMAD4 in tumor cell-free DNA of Brazilian pancreatic adenocarcinoma patients using next-generation sequencing — NSCLC
• ALK inhibitor–induced transformation of ALK fusion–positive lung adenocarcinoma to large cell neuroendocrine carcinoma — NSCLC
• Melanoma: Pathogenesis and Targeted Therapy — Melanoma
• EGFR deletion in myeloid cells reprograms the immunosuppressive landscape of colorectal cancer — Colorectal cancer
• MKRN2 enhances hepatocellular carcinoma proliferation through the p38 MAPK pathway — Hepatocellular carcinoma
• Next-generation CAR‑T therapy for acute myeloid leukemia: bridging innovation with clinical translation — Leukemia
• Invest where impact begins: recommendations from Breast Cancer Research Foundation Early Career Investigator Working Group (Part 1 of 2) — Breast cancer
• Clinically actionable molecular alterations in Rb-retained small cell lung carcinoma variants — SCLC
• International testing and refinement of AI algorithms predicting acute leukemia subtypes from routine laboratory data — Leukemia
• Projected Colorectal Cancer Detection Rates in Adults Under Age 45 — Colorectal cancer