Kutatási jelek – Signal Engine

• Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Landscape Analysis of Global Clinical Trials Based on Public Registries — Chronic myeloid leukemia
• Randomized, multicenter phase 3 study evaluating radiotherapy versus concurrent chemoradiotherapy in nasopharyngeal carcinoma patients achieving CR/PR after induction chemotherapy — Nasopharyngeal carcinoma
• Personalized targeting of BCL2 family proteins overcomes acquired resistance to BRAF-MEK inhibitors in preclinical melanoma — Melanoma
• Disrupting SOX2 self-association and condensate formation to overcome chemotherapeutic drug resistance in lung squamous cell carcinoma — NSCLC
• Non‑enzymatic function of QSOX2 directly regulates the JUNB‑ITGB4 axis and enhances resistance to osimertinib in EGFR‑mutation lung adenocarcinoma — NSCLC
• Prevalence and characterization of germline RAS pathway variants in children with chronic myeloid leukemia — Chronic myeloid leukemia
• Moving Beyond Morphology: Toward a Morpho‑Molecular Classification of Pleural Mesothelioma — Malignant pleural mesothelioma
• Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer — Head and neck squamous cell carcinoma
• The molecular mechanisms and potential therapeutic implications of the crosstalk between DNA methylation and metabolic reprogramming in thyroid cancer — Thyroid cancer
• HER3 beyond the canonical paradigm: a versatile signaling hub in oncogenesis and therapeutic resistance — Head and neck squamous cell carcinoma
• Off-trial outcomes of zanubrutinib in Waldenström macroglobulinemia: the prognostic impact of CXCR4 and TP53 alterations — Chronic lymphocytic leukemia
• The Evolving Therapeutic Revolution in Adult Acute Lymphoblastic Leukemia — Acute lymphoblastic leukemia
• Efficacy of PD-1 inhibitor plus induction chemotherapy for nasopharyngeal carcinoma with high-grade extranodal extension: a multicenter retrospective analysis — Nasopharyngeal carcinoma
• Anti‑PD‑1 antibody penpulimab plus chemotherapy for recurrent or metastatic nasopharyngeal carcinoma: a randomized, double‑blind phase 3 study — Nasopharyngeal carcinoma
• Targeted immunotherapies for anaplastic lymphoma kinase-positive pediatric tumors: current advances and future perspectives — Neuroblastoma
• Coexpression of MYCN and ALK Induces Neuroblastoma-Like Tumors From Human iPS Cell-Derived Cranial Neural Crest Cells. — Neuroblastoma
• Expert consensus on the role of immunotherapy in nasopharyngeal carcinoma: clinical and economic perspectives from the GCC region — Nasopharyngeal carcinoma
• Hierarchical dynamic model for risk‑stratified screening of nasopharyngeal carcinoma — Nasopharyngeal carcinoma
• Clinical Trials Update in Resectable Esophageal Cancer — Esophageal cancer
• Emerging treatment options for nasopharyngeal carcinoma — Nasopharyngeal carcinoma