Prevalence and characterization of germline RAS pathway variants in children with chronic myeloid leukemia
Germline variants in RAS pathway genes are prevalent in pediatric chronic myeloid leukemia and may predispose to early disease onset.
Identifying germline RAS pathway variants in pediatric CML patients highlights a potential genetic predisposition to early-onset disease, informs risk stratification, and may guide personalized therapy and surveillance strategies.
Bizonyítékszint: Sejtvonalas. Laboratóriumi sejtekben vizsgálták.
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