Immunotherapy improves endometrial cancer outcomes
Combining lenvatinib with pembrolizumab improves progression‑free and overall survival compared with chemotherapy in patients with advanced endometrial cancer.
This phase‑3 trial demonstrates that lenvatinib combined with the immune checkpoint inhibitor pembrolizumab provides a clinically meaningful benefit in survival outcomes for patients whose advanced endometrial cancer has progressed after platinum‑based chemotherapy, offering a new standard of care option in this setting.
Bizonyítékszint: Megerősített klinikai bizonyíték. Több vagy erősebb humán vizsgálat támogatja.
Kapcsolódó jelek
- Quality of Life Measures in Advanced Endometrial Cancer: A Systematic Review of Reporting Practices in Phase III Clinical Trials
- Endometrial Cancer - PMC
- Current recommendations and recent progress in endometrial cancer
- Advancements in Endometrial Cancer Research in 2024
- Selinexor Maintenance Improves PFS in TP53 Wild-Type Endometrial Cancer