Hilar cholangiocarcinoma: diagnosis, treatment options, and management

Cancer research · Cholangiocarcinoma

Hilar cholangiocarcinoma is a rare disease with a poor prognosis and typically presents in the 6th decade of life.

Hilar cholangiocarcinoma (HC) is a rare disease with a poor prognosis which typically presents in the 6th decade of life. Of the 3,000 cases seen annually in the United States, less than one half of these tumors are resectable. A variety of risk factors have been associated with HC, most notably primary sclerosing cholangitis (PSC), biliary stone disease and parasitic liver disease. Patients typically present with abdominal pain, pruritis, weight loss, and jaundice. Computed topography (CT), magnetic resonance imaging (MRI), and ultrasound (US) are used to characterize biliary lesions. Endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous tran...

Hilar cholangiocarcinoma remains a therapeutic challenge due to its rarity, poor prognosis, and the fact that less than half of patients are resectable at diagnosis.

Evidence level: Irányelv / elfogadott gyakorlat. Magas szintű klinikai elfogadottság.

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