Kutatási jelek – Signal Engine

• Epstein‑Barr virus reprograms immune escape in nasopharyngeal carcinoma — Nasopharyngeal carcinoma
• Management of Differentiated Thyroid Cancer — Thyroid cancer
• Acquired Squamous Transformation after Long-Term Osimertinib in EGFR-Mutant Lung Adenocarcinoma with Retained EGFR/TP53 Alterations — NSCLC
• Clinical patterns, treatment outcomes and determinant factors in children with neuroblastoma in a tertiary referral hospital in Ethiopia — Neuroblastoma
• Recent advances in molecular classification and multimodal treatment of intrahepatic cholangiocarcinoma — Cholangiocarcinoma
• Clinical implications of plasma EGFR T790M and ctDNA shedding across metastatic sites in plasma- or tissue-confirmed EGFR-mutant non-small cell lung cancer treated with lazertinib: a prospective multicenter cohort study — NSCLC
• EGFR G719X + S768I co‑mutations in NSCLC: genomic landscape and differential responses to EGFR‑TKIs in a large real‑world cohort — NSCLC
• Esophageal cancer: from pathogenesis to precision therapies — Esophageal cancer
• Genomic profiling enables personalized strategies to overcome drug resistance in multiple myeloma — Multiple myeloma
• CZC54252 overcomes Osimertinib resistance by targeting EGFR C797S mutations in NSCLC — NSCLC
• Variant allele frequency as a predictor of treatment response to osimertinib in EGFR‑mutated NSCLC — NSCLC
• Oncocytic adrenocortical carcinoma: A case report — Adrenocortical carcinoma
• Osimertinib plus datopotamab deruxtecan in patients with EGFR-mutated advanced NSCLC after progression on first-line osimertinib: ORCHARD — NSCLC
• Toward a cure for multiple myeloma within a decade — Multiple myeloma
• Targeted therapies in pediatric B-Cell acute lymphoblastic leukemia: mechanisms, efficacy, and future directions — Acute lymphoblastic leukemia
• Drug sensitivity testing of patient-derived bone sarcomas identifies selective kinase inhibitors for patients with refractory disease — Osteosarcoma
• Varnimcabtagene autoleucel (ARI‑00001) in relapsed or refractory mantle cell lymphoma — Mantle cell lymphoma
• Prognostic impact of somatic mutations among patients with pleural and peritoneal mesothelioma — Malignant pleural mesothelioma
• Geospatial Access to CAR‑T Clinical Trials for Non‑Hodgkin Lymphoma for Persons With HIV — Diffuse large B-cell lymphoma
• Normal Ovarian Reserve During Long‑Term Osimertinib Therapy in a Patient With Li‑Fraumeni Syndrome — NSCLC