A randomised controlled non-inferiority trial to compare the efficacy of ‘HPV screen, triage and treat’ with ‘HPV screen and treat’ approach for cervical cancer prevention among women living with HIV
We report results of a randomized controlled trial to compare “HPV screen and treat” (Arm 1) and “HPV screen, triage and treat” (Arm 2) in women living with HIV (WLHIV), using visual inspection with acetic acid (VIA) as the triaging test.
We report results of a randomized controlled trial to compare “HPV screen and treat” (Arm 1) and “HPV screen, triage and treat” (Arm 2) in women living with HIV (WLHIV), using visual inspection with acetic acid (VIA) as the triaging test.
Cervical cancer remains a leading cause of morbidity and mortality among women living with HIV. This study directly compared two screening–treatment algorithms to determine whether a triage step is necessary, addressing a critical gap in evidence for optimal care pathways in high‑risk populations, particularly in low‑ and middle‑income settings where resource allocation must be judicious.
Evidence level: Korai humán adat. Kis vagy feltáró emberi adat.
Related signals
- A multinational cross-sectional study on human papillomavirus and cervical cancer knowledge, vaccination attitudes, and risk factors in the Middle East
- Genomic features of cervical cancer
- Screening for Cervical Cancer
- Cervical cancer: Epidemiology, risk factors and screening
- AI approach outperformed human experts in identifying cervical precancer