Clinical implications of plasma EGFR T790M and ctDNA shedding across metastatic sites in plasma- or tissue-confirmed EGFR-mutant non-small cell lung cancer treated with lazertinib: a prospective multicenter cohort study
Baseline plasma EGFR T790M positivity is associated with significantly shorter progression‑free survival and overall survival in EGFR‑mutant NSCLC patients treated with lazertinib, especially when liver or adrenal metastases are present.
Evidence level: Klinikai vizsgálat. Formális klinikai vizsgálati eredmény.
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