Natural products targeting the molecular pathology of salivary gland mucoepidermoid carcinoma: A systematic review of In vitro studies
Natural products exhibit antiproliferative and proapoptotic activity in a mucoepidermoid carcinoma model by targeting several converging survival pathways.
Mucoepidermoid carcinoma of the salivary glands has limited systemic treatment options, while natural products have the potential to inhibit tumor survival by modulating multiple molecular pathways. This study aims to elucidate the antitumor activity, biological mechanisms, and translational potential of natural products in a preclinical model of mucoepidermoid carcinoma.
Natural products routinely inhibit tumor survival in vitro and in vivo by targeting several converging survival pathways in systems that ultimately lead to potential development of clinically relevant compounds.
Evidence level: Korai humán adat. Kis vagy feltáró emberi adat.
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