Acquired Squamous Transformation after Long-Term Osimertinib in EGFR-Mutant Lung Adenocarcinoma with Retained EGFR/TP53 Alterations

Cancer research · NSCLC · EGFR · TP53 · osimertinib

Acquired squamous histological transformation after long-term osimertinib treatment in EGFR-mutant lung adenocarcinoma with retained EGFR/TP53 alterations.

This case underlines the necessity of re‑biopsy to detect histological transformations in EGFR‑mutant NSCLC, influencing subsequent therapeutic decisions.

Evidence level: Korai humán adat. Kis vagy feltáró emberi adat.

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