Association of rituximab with survival outcomes in primary testicular diffuse large B-cell lymphoma: a systematic review and meta-analysis of retrospective studies
This systematic review and meta-analysis aimed to evaluate the association between rituximab-containing frontline therapy and clinical outcomes in patients with PT-DLBCL.
Primary testicular diffuse large B-cell lymphoma (PT-DLBCL) is the most common subtype of primary testicular lymphoma. Standard treatment protocols generally encompass a multimodal approach, incorporating radical orchiectomy, rituximab-based chemotherapy, prophylactic radiotherapy, and central nervous system (CNS) prophylaxis. However, whether rituximab-containing therapy is associated with survival outcomes in patients with PT-DLBCL remains uncertain. This systematic review and meta-analysis aimed to evaluate the association between rituximab-containing frontline therapy and clinical outcomes in patients with PT-DLBCL.
Bizonyítékszint: Sejtvonalas. Laboratóriumi sejtekben vizsgálták.
Kapcsolódó jelek
- Diffuse Large B‑Cell Lymphoma – Global Clinical Trial Landscape (2024)
- Mantle‑Cell Lymphoma (MCL)
- Inhibition of autoantigen‑induced B‑cell receptor (BCR) internalization as a therapeutic strategy in diffuse large B cell lymphoma (DLBCL)
- Successful treatment of primary refractory DLBCL/HGBL - MYC/BCL2 transformed from FL using glofitamab: a case report
- Loncastuximab in high‑risk and heavily pre‑treated relapsed/refractory diffuse large B‑cell lymphoma: a real‑world analysis from 21 US centers