AbbVie Announces Positive Phase 3 Results for Epcoritamab Plus Lenalidomide in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Cancer research · Diffuse large B-cell lymphoma

Topline results from Phase 3 EPCORE DLBCL‑4 trial evaluating epcoritamab in combination with lenalidomide demonstrated statistically significant and clinically meaningful improvement in progression‑free survival (PFS) in patients with relapsed or refractory diffuse large B‑cell lymphoma (DLBCL).

Topline results from the Phase 3 EPCORE DLBCL‑4 trial evaluating epcoritamab plus lenalidomide versus standard chemoimmunotherapy (R‑GemOx) in adult patients with relapsed or refractory Diffuse Large B‑cell Lymphoma demonstrated a statistically significant and clinically meaningful improvement in progression‑free survival.

These results represent a promising new therapeutic option for patients with relapsed or refractory DLBCL, a disease that historically carries limited treatment choices and poor outcomes.

Evidence level: Irányelv / elfogadott gyakorlat. Magas szintű klinikai elfogadottság.

Original source

Related signals