Uveal Melanoma
Tebentafusp is an immunotherapy (a bispecific gp100 peptide-HLA‑directed CD3 T‑cell engager) that has been approved by the US Food and Drug Administration to treat certain patients with unresectable or metastatic uveal melanoma.
The approval of tebentafusp represents a significant therapeutic advance for patients with metastatic uveal melanoma, a disease that historically has very limited systemic treatment options and poor survival outcomes.
Evidence level: Megerősített klinikai bizonyíték. Több vagy erősebb humán vizsgálat támogatja.
Related signals
- Beyond the Five-Year Milestone: Long‑term Survivorship of Melanoma Patients Treated Off‑Trial with anti‑PD‑1
- Uveal Melanoma – Trials in Disease – Overview of Information and Clinical Research
- A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
- Melanoma Research
- The Clinical Trial Landscape for Melanoma Therapies