Osteosarcoma Treatment & Management: Approach Considerations, Pharmacologic Treatment, Biopsy
Before the use of chemotherapy (which began in the 1970s), osteosarcoma was treated primarily with surgical resection (usually amputation).
Chemotherapy is essential for systemic control because most patients present with micrometastatic disease; surgical resection alone provides good local control but is insufficient to prevent widespread recurrence.
Bizonyítékszint: Sejtvonalas. Laboratóriumi sejtekben vizsgálták.
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- Potential proteins identified to target in osteosarcoma treatment
- Future Directions in the Treatment of Osteosarcoma
- Is There a Role for Mifamurtide in Nonmetastatic High‑Grade Osteosarcoma? Results From the Italian Sarcoma Group (ISG/OS‑2) and Spanish Sarcoma Group (GEIS‑33) Trials
- The clinical trial landscape of osteosarcoma: integrating trial data, immunotherapeutic trends, and biomarker insights