Extended Access of Momelotinib in Adults With Myelofibrosis
Extended access is designed to evaluate the long‑term safety and efficacy of momelotinib in adults with myelofibrosis by continuing treatment and monitoring overall survival and leukemia‑free survival.
This Phase 2 study is an extended‑access program for adults with myelofibrosis who are already taking momelotinib in other studies. It aims to monitor the long‑term safety of momelotinib, as well as its impact on overall survival and the prevention of progression to leukemia.
Ensures patients who benefit from momelotinib can continue treatment while providing data on long‑term safety and effectiveness, which is crucial for clinical decision‑making.
Evidence level: Állatkísérletes. Állatmodellben vizsgálták.
Related signals
- ASH 2024: New Research, Data Drive Progress in Myelofibrosis
- Single agent selinexor is active in patients with myelofibrosis refractory or intolerant to JAK inhibitors
- Population Pharmacokinetics and Exposure‑Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis
- SOHO 2026: Imetelstat Efficacy in Myelofibrosis - GERN
- Current treatments, practical management, and emerging investigational therapies for myelofibrosis