International Delphi-based consensus: therapeutic approaches for pediatric adrenocortical carcinoma

Cancer research · Adrenocortical carcinoma

"Complete surgical resection remains the cornerstone of curative intent therapy, and complete adrenalectomy offers the best chance for long-term survival."

The consensus aimed to create international guidance for treating pediatric adrenocortical carcinoma (ACC). A modified 3‑step Delphi method was used with an international panel of experts. Consensus statements were produced for surgical and medical therapy across disease stages. The guideline emphasizes complete surgical resection (complete adrenalectomy) as the cornerstone of curative intent therapy, with adjuvant treatments considered for advanced disease.

The statement identifies complete adrenalectomy as the most effective curative treatment for pediatric ACC and serves as the central recommendation of the consensus guideline.

Evidence level: Klinikai vizsgálat. Formális klinikai vizsgálati eredmény.

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