Prediction model for survival outcome in patients with acute myeloid leukemia: a multicenter prospective cohort study from Thai Acute Leukemia Working Group
The study aimed to evaluate the predictive factors for death and generate a model to predict survival in patients with AML.
Despite the development of advanced therapeutic approaches in the last two decades, acute myeloid leukemia (AML) has a poor prognosis, especially in older patients. The main causes of death are refractory/relapsed disease, fatal bleeding, or serious infection. A model to predict survival in patients with AML is necessary for clinicians to make decisions regarding appropriate treatment. In this study, we aimed to evaluate the predictive factors for death and generate a model to predict survival in patients with AML.
A reliable prognostic model enables clinicians to stratify patients, tailor therapies (e.g., intensive chemotherapy, allogeneic stem cell transplantation, or palliative care), and improve resource allocation and shared decision‑making for patients with AML.
Bizonyítékszint: Korai humán adat. Kis vagy feltáró emberi adat.
Kapcsolódó jelek
- Management of Acute Myeloid Leukemia: A Review
- Old cells, new tricks—important clue to AML diagnosis and cure discovered
- Treatment of Acute Myeloid Leukaemia
- Effective eradication of acute myeloid leukemia stem cells with FLT3-directed antibody-drug conjugates
- Research blog: Accelerating progress in AML