Brentuximab vedotin and nivolumab in combination with chemotherapy for nonbulky, nearly-stage classical Hodgkin lymphoma
The study demonstrates high efficacy and acceptable safety of the combination of brentuximab vedotin and nivolumab with doxorubicin and dacarbazine (AN+AD) in patients with early‑stage classical Hodgkin lymphoma.
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The trial indicates that adding novel immunotherapies to abbreviated chemotherapy can achieve near‑complete cure rates while potentially reducing treatment intensity and long‑term toxicity in early‑stage classical Hodgkin lymphoma.
Bizonyítékszint: Korai humán adat. Kis vagy feltáró emberi adat.
Kapcsolódó jelek
- Advanced Classical Hodgkin Lymphoma Management in East and Southeast Asia: Real-World Challenges and Aspirations of the Asian Lymphoma Study Group.
- Overcoming PD‑1 Resistance in Relapsed/Refractory Hodgkin Lymphoma
- Progress in the Treatment of Advanced-Stage Classical Hodgkin Lymphoma in the PET-Adapted Era
- Late cardiopulmonary morbidity in patients with Hodgkin lymphoma: a retrospective nationwide registry study
- Combination of Acimtamig and AlloNK Effective in R/R Classical Hodgkin Lymphoma