Total body irradiation versus chemotherapy before stem cell transplantation in children aged two to four with acute lymphoblastic leukemia—an EBMT pediatric diseases working party study
Total body irradiation versus chemotherapy before stem cell transplantation in children aged two to four with acute lymphoblastic leukemia
The study evaluates whether total body irradiation (TBI)-based conditioning or chemotherapy (CTx)-based conditioning provides better outcomes in children aged 2–4 years with acute lymphoblastic leukemia (ALL) undergoing allo‑hematopoietic stem cell transplantation, addressing the crucial balance between long‑term toxicity (e.g., subsequent malignant neoplasms) and disease control.
Bizonyítékszint: Sejtvonalas. Laboratóriumi sejtekben vizsgálták.
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