Radiation Therapy for Anal Squamous Cell Carcinoma: An ASTRO Clinical Practice Guideline
Definitive combined modality therapy using concurrent 5‑fluorouracil or capecitabine plus mitomycin, with cisplatin as a conditional alternative, is recommended for most patients with anal squamous cell carcinoma.
This guideline provides evidence-based recommendations addressing the indications for definitive treatment of primary squamous cell carcinoma of the anal canal and anal margin.
Providing evidence-based guidance improves clinical decision‑making for anal squamous cell carcinoma, optimizing treatment efficacy while minimizing toxicity.
Bizonyítékszint: Számítógépes vagy elméleti. Modellből vagy adatbányászatból származó jel.
Kapcsolódó jelek
- Clinical Outcomes, Patterns of Failure, and Salvage Therapies of a Large Modern Cohort of Patients With Anal Squamous Cell Carcinoma Treated With Definitive-Intent Intensity‑Modulated Radiation Therapy
- Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer
- Advancements in Immunotherapy for Anal Cancer Treatment
- Background and Current Treatment of Squamous Cell Carcinoma of the Anus
- Genotyping and Cytology Co-Testing for Anal Cancer Screening: Exploratory Evaluation of Cumulative HPV Genotype Burden