Prostate Cancer
Prostate cancer is the most commonly diagnosed malignancy worldwide and the sixth leading cause of cancer-related death in men.
This comprehensive review summarizes current knowledge on the epidemiology, risk factors, genetics, diet, and treatment options for prostate cancer. It highlights that prostate cancer is the most common malignancy among men worldwide, the burden of screening controversies, and the array of therapeutic modalities available for localized and metastatic disease. The review also discusses the influence of genetic predisposition—with emphasis on BRCA1/2, HOXB13, MSI pathway genes, and androgen‑related genes—on disease risk and progression, as well as lifestyle factors such as diet, vitamin D, and obesity. Potential protective effects of statins, metformin, and NSAIDs are considered, along with the evolving role of molecular diagnostics.
Prostate cancer remains the leading cancer among men and a major cause of morbidity and mortality. Understanding its epidemiology, risk factors, and therapeutic landscape is essential for clinicians, patients, and researchers to improve early detection, personalize treatment, and reduce mortality.
Bizonyítékszint: Korai humán adat. Kis vagy feltáró emberi adat.
Kapcsolódó jelek
- Apalutamide Treatment and Metastasis‑free Survival in Prostate Cancer
- The prostate cancer conundrum revisited: Treatment changes and prostate cancer mortality declines
- The contemporary management of prostate cancer
- Extracellular TROP2 Fragment Identified as a Potential Biomarker and Metastasis Driver
- Overall survival of prostate cancer patients treated with Lu‑177 PSMA 617 (Pluvicto®) in a multidisciplinary setting— a single center experience