Frontiers | Research progress of tertiary lymphoid structure in hepatocellular carcinoma: from prognostic biomarkers to new strategies for immunotherapy
Tertiary lymphoid structures have significant prognostic value in hepatocellular carcinoma.
Tertiary lymphoid structures (TLS) are important ectopic immune aggregates that develop within the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) and have attracted increasing attention due to their potential clinical value. Recent studies have identified TLS as key players in prognosis assessment and immunotherapy response prediction in HCC, with their maturity and spatial distribution being critical determinants of clinical outcomes. ...
201.17\u2029Averaging5.89\u2029Validate7.76\u2029Hypothesis5.36\u2029probabilistic Would you like to inquire more about the evidence supporting this claim?
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