Treating the invisible target: treatment planning targeting the microscopic tumor spread in gliomas
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, but treatment outcome is poor, and tumor recurrence is often unavoidable.
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, but treatment outcome is poor, and tumor recurrence is often unavoidable. Evidence suggests that regions with tumor cell densities below the medical imaging visibility threshold are more prevalent than the current treatment methodologies account for. This study aimed to explore different treatment planning strategies that account for the microscopic tumor cell distribution.
Studying treatments that target microscopic tumor spread may improve local control and survival for patients with GBM.
Evidence level: Korai humán adat. Kis vagy feltáró emberi adat.